Pickups

There are a variety of items that the player can find throughout the Facility. Most commonly, players will find debris, health, weapon ammunition, and bombs. Less frequently, for instance, maximum health upgrades and damage increases can be found.

Various factors play into the frequency and types of pickups the player will find including the possession of certain upgrades and cartridges.

Pickups are contained within floating bubbles that the player can collide with to collect. When the player leaves the room, any items that are left behind will disappear. The exception to this rule are bubbles with a small lock at their base and reliquary blessings, which will be present in the room after the player returns.

All pickups, including those added in Relics of the Past, are unlocked by default, except for several Power Bombs that must be unlocked individually.

Debris
Debris are the currency used to buy goods at shops. The amount of debris dropped by enemies varies and is influenced by the player's current multiplier. Debris can also be obtained by scrapping weapons, picking up certain pickups past their maximum allowed amount, or by obtaining items that turn into debris upon pickup. The amount of debris salvaged by these items is not affected by the player's current multiplier, unlike those dropped by enemies. Instead, the amount salvaged is dependent on the floor the player is present on when collecting the item. Note that Floor 7 is actually counted for all ingame effects that scale by floor as an 8th floor, due to the transitional floor between Floor 6 and it. This in-between floor exists to contain the Monolith fight/Power Eternal conduit, depending on the player's selected difficulty.

Health
Health pickups come in a variety of forms ranging from health parts to maximum health increases.

Ammo
Ammo pickups either refill the player's weapon ammunition or increase the player's maximum ammo capacity.

Bombs
Bombs are used to destroy all bullets on-screen or to blow open walls that lead to shortcuts or secrets. By default, the player starts the game with two rechargeable bombs. When one of these bombs is used, it can be recharged by clearing enemies from three rooms. This recharge period can be reduced to two rooms if the player has the Battery cartridge. The players rechargeable bomb capacity can also be increased from two to three if they obtain the Extra Pow upgrade. At any point, the player can hold up to six bombs total.

In addition to normal bombs, there are several special Power bombs that produce an additional effect depending on their type, as well as dealing a small amount of damage. Three types are unlocked by default, but most must be unlocked and then purchased from Kleines's shop to appear in runs. Bombs that must be unlocked can be toggled off, but ones that are unlocked by default cannot.

The player's current bombs are displayed in the top-left region of the HUD. Normal bombs are indicated via the color yellow, and each Power bomb has a different color associated with it. When a rechargeable bomb has been used and the player's current bomb count is less than their total rechargeable bomb count, an outline will be left in its place. This icon will gradually fill as the player clears rooms of enemies, until the bomb is recharged. It is possible to have a partially charged bomb be kept after you pick up a bomb that puts you at the rechargeable bomb limit, though it cannot be used in its current state and will not charge further until you have used enough bombs to open up a slot.

Arena Blaster cannot obtain bombs in any form, instead carrying active items, detailed on that ship's page.

Damage Up
Damage increases are a rare pickup that players can obtain either by purchase, by locating them in secret rooms, or receive upon defeating a boss. The pickup affects both the player's default weapon and any weapons picked up as a bonus additive to that which they already have. As the player obtains more damage, the likelihood of finding these pickups lowers.

Skully cannot obtain Damage pickups, though they may increase their damage in other ways.

Crates
Crates can either be found as a reward for clearing a room or within a shortcut. Players can unlock crates by sacrificing a percentage of their weapon's maximum ammo. If they do not possess a weapon or their does not have ammo, such as from curses, they will be unable to open the crate.

Weapons
Weapons, while most commonly found within Weapon Troves (a guaranteed room on many floors), can also be found as Pickups in a variety of locations and scenarios. There are 13 different types of weapons that can be found, each with their own unique properties, affected by a variety of Keywords. Each weapon type also has a variety of unique variants that are fairly rare to find, produce special effects, and typically boast improved damage at the cost of a lower total ammo count.

Meta-Game Items
Some items found within the depths of the Facility have special purposes that do not necessarily assist the player in their current run.

Seals
After the player has defeated Overlord once, they can begin finding and collecting Seals. When all Seals have been collected, the door leading to Floor 6 will be unlocked, allowing the player to advance their run after defeating Overlord.